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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA3 All Species: 36.97
Human Site: S169 Identified Species: 50.83
UniProt: P30101 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P30101 NP_005304.3 505 56782 S169 D S F S E A H S E F L K A A S
Chimpanzee Pan troglodytes XP_001159528 485 54945 S149 D S F S E A H S E F L K A A S
Rhesus Macaque Macaca mulatta XP_001108948 480 54081 S144 D L F S E A H S E F L K A A S
Dog Lupus familis XP_535453 687 75990 S351 D L F S E A H S E F L K A A S
Cat Felis silvestris
Mouse Mus musculus P27773 505 56660 S169 D L F S D G H S E F L K A A S
Rat Rattus norvegicus P11598 505 56605 S169 D L F S D G H S E F L K A A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517928 483 54617 S146 D L F S E A H S E F L K A A S
Chicken Gallus gallus Q8JG64 505 56163 S167 D A S G D A Y S E F M K A A N
Frog Xenopus laevis NP_001080051 502 56103 S165 D L Y S G P H S E F L K A A N
Zebra Danio Brachydanio rerio NP_998070 488 54656 A161 G E D S A Q L A E F L K A S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 T171 L E S E E A K T F T K V A N A
Honey Bee Apis mellifera XP_623282 490 55838 T166 K E D L S L A T T F H A V S K
Nematode Worm Caenorhab. elegans P34329 618 69779 A291 E D S T A F E A F S D S A E M
Sea Urchin Strong. purpuratus XP_782981 472 51996 K160 D E T S A G L K E F K K L T D
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 T181 E F S G T E F T N F M E V A E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 D176 K L S G D E F D S F M A L A E
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 N174 G K I D A D F N A T F Y S M A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 94.4 70.8 N.A. 93 92.2 N.A. 84.7 80.9 74.6 60 N.A. 32.6 49.5 36.7 50.5
Protein Similarity: 100 92.6 94.8 72.1 N.A. 97 96.2 N.A. 90.3 90.8 88.3 77.2 N.A. 53.4 63.7 50.4 65.9
P-Site Identity: 100 100 93.3 93.3 N.A. 80 80 N.A. 93.3 53.3 66.6 46.6 N.A. 20 6.6 6.6 33.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 93.3 86.6 80 60 N.A. 33.3 20 26.6 33.3
Percent
Protein Identity: N.A. 34.3 N.A. 35.6 26.8 N.A.
Protein Similarity: N.A. 51 N.A. 54.9 48.4 N.A.
P-Site Identity: N.A. 13.3 N.A. 13.3 0 N.A.
P-Site Similarity: N.A. 40 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 0 24 42 6 12 6 0 0 12 71 65 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 59 6 12 6 24 6 0 6 0 0 6 0 0 0 6 % D
% Glu: 12 24 0 6 36 12 6 0 65 0 0 6 0 6 12 % E
% Phe: 0 6 42 0 0 6 18 0 12 83 6 0 0 0 0 % F
% Gly: 12 0 0 18 6 18 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 48 0 0 0 6 0 0 0 0 % H
% Ile: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 6 0 0 0 0 6 6 0 0 12 65 0 0 6 % K
% Leu: 6 42 0 6 0 6 12 0 0 0 53 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 18 0 0 6 6 % M
% Asn: 0 0 0 0 0 0 0 6 6 0 0 0 0 6 12 % N
% Pro: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 30 59 6 0 0 53 6 6 0 6 6 12 48 % S
% Thr: 0 0 6 6 6 0 0 18 6 12 0 0 0 6 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 6 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 6 0 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _